Poloxamer 407

0-6 month old newbornsSkin contact product

Check for Different Age (6 available)

Is this safe for 0-6 month old newborns to use Poloxamer 407?

YES - Generally Safe
Danger Score: 3 (Lower is safer)
Quick Answer: Poloxamer 407 is generally considered safe for 0-6 month old babies when used in topical products. Always consult your pediatrician for newborns.

ℹ️General Overview

For newborns and babies (0-6 months), Poloxamer 407 is usually low risk and is used to help clean skin. But there are gaps in safety testing and an environmental health agency raised some concerns, so we should be careful with very young babies.

What to Do

Use only baby-formulated products that list this ingredient. Use small amounts, avoid applying to broken or irritated skin, keep it away from the baby’s mouth and eyes, and rinse off if you notice any irritation. If you want to be extra cautious, choose products that do not list this ingredient or look for products that have specific safety data for infants.

⚠️Warnings

Safety reviewers in the cosmetic industry have noted missing direct safety data and that some assessments rely on related chemicals (Cosmetic industry review). An environmental health agency reported concerns about persistence in the environment and possible organ effects (Environment Canada). Also note that some product certification programs restrict use of this ingredient unless manufacturers provide extra safety data. Watch for redness, rash, fussiness after use, or any signs the product got in the mouth or eyes, and stop use and see your pediatrician if those happen.

Confidence: MEDIUM

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Safety Risk Labels

This ingredient has the following documented risks:

Organ Risk: Environment Canada reviewed this ingredient and flagged it as likely to be toxic or harmful to non-reproductive organs and gave it a medium human-health priority. That means repeated or large exposures could harm organs like the liver or kidneys, according to that assessment.
Builds Up: Environment Canada identified this substance as persistent and potentially bioaccumulative with a moderate-to-high toxicity concern. Persistent and bioaccumulative substances can collect in the body over time with repeated use, which raises long‑term exposure worries.
Environmental: An environmental review found this ingredient is suspected to be an environmental toxin and raised ecotoxicology concerns. This means it may harm wildlife or persist in the environment after use.
Long-Term Risk: Because regulators have noted persistence, possible buildup, and organ toxicity potential, there is a plausible link to longer-term health effects from repeated exposure. The cosmetic safety review also notes data gaps, so long-term effects are not fully ruled out.

Tap or hover over labels to see detailed risk information.

Alternative Names for Poloxamer 407

This ingredient may also be listed as:

poloxamer 407UNII-52901V8XARPROPYLENE OXIDE ETHYLENE OXIDE75-H-1400OXIRANE, POLYMER WITH OXIRANE.ALPHA.-HYDRO-.OMEGA.-HYDROXYPOLY(OXYETHYLENE)POLY(OXYPROPYLENE)POLY(OXYETHYLENE) BLOCK COPOLYMERALPHA-HYDRO-OMEGA-HYDROXYPOLY(OXYETHYLENE)A-POLY(OXOPROPYLENE)B-POLY(OXYETHYLENE)A BLOCK COPOLYMERADEKA PLURONIC F-108ETHYLENE OXIDE PROPYLENE OXIDE199SZS8E2QTSL 431

Always check ingredient labels carefully, as ingredients may be listed under different names.

Common Questions About Poloxamer 407

Is this ingredient safe for newborns to use Poloxamer 407?

Yes, Poloxamer 407 is generally considered safe for 0-6 month old babies based on current research.

What are the organ risk risks of Poloxamer 407 for newborns?

May harm organs like liver, kidneys, or lungs with repeated use. This is especially important for babies whose skin and systems are still developing.

What are the builds up risks of Poloxamer 407 for newborns?

Builds up in the body over time with repeated use. This is especially important for babies whose skin and systems are still developing.

What are the environmental risks of Poloxamer 407 for newborns?

Possible negative effects on the environment This is especially important for babies whose skin and systems are still developing.

What are the long-term risk risks of Poloxamer 407 for newborns?

Linked to long-term health effects after years of use or exposure. This is especially important for babies whose skin and systems are still developing.

What products contain Poloxamer 407?

Poloxamer 407 is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.

When can infants start using products with Poloxamer 407?

The appropriate age depends on the specific ingredient properties and concentration. This analysis is for 0-6 month old babies. Use the age selector above to check other ages.

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