Protease

Protease molecular structure

0-6 month old newborns • Skin contact product

Check for Different Age (6 available)

Is this safe for 0-6 month old newborns to use Protease?

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NOT RECOMMENDED
Danger Score: 7 (Lower is safer)
Quick Answer: Protease not recommended for 0-6 month old babies when used in topical products. Always consult your pediatrician for newborns.

ℹ️General Overview

For newborns and babies 0–6 months, protease is not a good choice for skin products. It can trigger allergic reactions and irritate very young, thin skin.

✅What to Do

Avoid skincare or topical products that list protease (or bacterial protease) on the label for infants and newborns. Use gentle, plain, fragrance‑free products made for babies. If a product containing protease was accidentally applied, rinse the area with water and stop using it. Call your baby’s pediatrician if you see redness, swelling, blisters, or any breathing trouble.

⚠️Warnings

Watch for rash, redness, hives, swelling, or any breathing changes after exposure — peer‑reviewed studies identify protease as a human allergen. Also note that some product safety programs restrict this ingredient unless makers can show it's safe, and the U.S. Food and Drug Administration only recognizes it for certain limited food uses, not routine topical use on infants.

Confidence: HIGH

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Safety Risk Labels

This ingredient has the following documented risks:

Immune system: Peer-reviewed studies show this protease acts as a human allergen and can trigger immune reactions. That means some people — including children with sensitive skin — could have allergic responses after using products that contain it.
Irritant: Because the ingredient can cause allergic reactions in people, it can also lead to skin redness, itching, or rashes when applied to the skin. This risk is supported by peer-reviewed literature reporting strong evidence of human allergen effects.
Eczema: Allergic or immune reactions to this protease can trigger or make eczema and similar skin conditions worse. Peer-reviewed sources note strong allergen evidence, which makes flare-ups more likely for children with eczema-prone skin.

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Alternative Names for Protease

This ingredient may also be listed as:

proteasePROTEASEBACILLUS SUBTILIS NEUTRAL PROTEASEA.S. 1.398BACTERIAL PROTEASE

Always check ingredient labels carefully, as ingredients may be listed under different names.

Common Questions About Protease

Is this ingredient safe for newborns to use Protease?

Protease is not recommended for 0-6 month old babies due to potential safety risks.

What are the immune system risks of Protease for newborns?

Could weaken or confuse immune system. This is especially important for babies whose skin and systems are still developing.

What are the irritant risks of Protease for newborns?

Can cause skin redness, itchiness, or rashes—especially on sensitive baby skin. This is especially important for babies whose skin and systems are still developing.

What are the eczema risks of Protease for newborns?

Linked to triggering or worsening eczema and similar skin conditions. This is especially important for babies whose skin and systems are still developing.

What products contain Protease?

Protease is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.

When can infants start using products with Protease?

The appropriate age depends on the specific ingredient properties and concentration. This analysis is for 0-6 month old babies. Use the age selector above to check other ages.

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