Trisodium Ethylenediamine Disuccinate

0-6 month old newbornsSkin contact product

Check for Different Age (6 available)

Is this safe for 0-6 month old newborns to use Trisodium Ethylenediamine Disuccinate?

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USE WITH CAUTION
Danger Score: 4 (Lower is safer)
Quick Answer: Trisodium Ethylenediamine Disuccinate use with caution for 0-6 month old babies when used in topical products. Always consult your pediatrician for newborns.

ℹ️General Overview

For newborns and young babies (0–6 months) this ingredient is generally considered low risk in adult tests, but we are cautious. Studies show it can make skin absorb more and has caused irritation in animals, so it’s best to avoid regular use on very young babies.

What to Do

If possible, choose baby products that do not list this ingredient. If a product for babies does contain it, prefer rinse-off products (bath or shampoo) rather than creams or oils that stay on the skin. Don’t use it on broken or inflamed skin, keep it away from the eyes, and stop use and talk to your pediatrician if you see redness, swelling, rash, or any changes in your baby’s behavior after use.

⚠️Warnings

Peer-reviewed studies summarized in the ingredient safety information note two things to watch for: (1) it can increase skin absorption (so more of other ingredients might get through baby skin), and (2) animal tests showed eye and skin irritation at higher doses; there were also some lab tests showing mutation signals at high exposures. Because of these findings, avoid leave-on products with this ingredient on infants and be cautious even with rinse-off uses.

Confidence: MEDIUM

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Safety Risk Labels

This ingredient has the following documented risks:

Absorbed: Peer‑reviewed studies identify this chemical as a penetration enhancer. That means it can help other ingredients pass through the skin and enter the bloodstream, which raises how much a child can absorb from a product.
Irritant: Animal studies in the peer‑reviewed literature show eye irritation at high doses and skin irritation at moderate doses. On sensitive baby skin this could cause redness, stinging, or a rash.
Cancer: Lab tests on mammal cells reported mutation‑positive results in peer‑reviewed work. That finding raises a possible cancer concern, though it comes from cell studies rather than human tests.
Organ Risk: Peer‑reviewed animal studies found effects on the pancreas at high doses. This shows the ingredient can harm internal organs under strong or repeated exposure in those studies.
Fertility: Peer‑reviewed animal studies report developmental or reproductive effects at high doses. That suggests a possible risk to development or future fertility with large or repeated exposures in those tests.
Long-Term Risk: Taken together, cell tests showing mutations and animal studies showing organ and reproductive effects (all from peer‑reviewed sources) point to possible long‑term health concerns if exposure is repeated over time.

Tap or hover over labels to see detailed risk information.

Alternative Names for Trisodium Ethylenediamine Disuccinate

This ingredient may also be listed as:

trisodium ethylenediamine disuccinateSODIUM SALT ETHYLENEDIAMINE DISUCCINATEETHYLENEDIAMINE-N,N'-DISUCCINIC ACIDETHYLENEDIAMINEDISUCCINIC ACIDSCHEMBL39257ETHYLENEBISIMINODISUCCINIC ACIDQ412231N-{2-[(1,2-DICARBOXYETHYL)AMINO]ETHYL}ASPARTIC ACID2-[2-(1,2-DICARBOXYETHYLAMINO)ETHYLAMINO]BUTANEDIOIC ACIDEDDSTRISODIUM ETHYLENEDIAMINE DISUCCINATEtrisodium ethylene diamine disuccinatetriosodium ethylenediamine disuccinateTRESODIUM ETHYLENEDIAMINE DISUCCINATE

Always check ingredient labels carefully, as ingredients may be listed under different names.

Products Containing Trisodium Ethylenediamine Disuccinate

This ingredient is found in the following products:

This list shows products that contain Trisodium Ethylenediamine Disuccinate or its alternative names.

Common Questions About Trisodium Ethylenediamine Disuccinate

Is this ingredient safe for newborns to use Trisodium Ethylenediamine Disuccinate?

Use caution with Trisodium Ethylenediamine Disuccinate for 0-6 month old babies. Some safety concerns have been identified.

What are the absorbed risks of Trisodium Ethylenediamine Disuccinate for newborns?

Can be absorbed through the skin and get into the bloodstream. This is especially important for babies whose skin and systems are still developing.

What are the irritant risks of Trisodium Ethylenediamine Disuccinate for newborns?

Can cause skin redness, itchiness, or rashes—especially on sensitive baby skin. This is especially important for babies whose skin and systems are still developing.

What are the cancer risks of Trisodium Ethylenediamine Disuccinate for newborns?

Connected to cancer risk with long-term or repeated exposure. This is especially important for babies whose skin and systems are still developing.

What are the organ risk risks of Trisodium Ethylenediamine Disuccinate for newborns?

May harm organs like liver, kidneys, or lungs with repeated use. This is especially important for babies whose skin and systems are still developing.

What are the fertility risks of Trisodium Ethylenediamine Disuccinate for newborns?

Some studies link this to future fertility or reproductive issues. This is especially important for babies whose skin and systems are still developing.

What are the long-term risk risks of Trisodium Ethylenediamine Disuccinate for newborns?

Linked to long-term health effects after years of use or exposure. This is especially important for babies whose skin and systems are still developing.

What products contain Trisodium Ethylenediamine Disuccinate?

Trisodium Ethylenediamine Disuccinate is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.

When can infants start using products with Trisodium Ethylenediamine Disuccinate?

The appropriate age depends on the specific ingredient properties and concentration. This analysis is for 0-6 month old babies. Use the age selector above to check other ages.

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