Poloxamer 407

1-2 year old toddlersSkin contact product

Check for Different Age (6 available)

Is this toddler-safe to use Poloxamer 407?

YES - Generally Safe
Danger Score: 1 (Lower is safer)
Quick Answer: Poloxamer 407 is generally considered safe for 1-2 year old toddlers when used in topical products. Watch for toddler-specific sensitivities.

ℹ️General Overview

For toddlers (1-2 years), Poloxamer 407 is generally low risk when used on the skin in small amounts. It is commonly found in baby wipes and gentle lotions and is not usually linked to cancer or strong allergy risk. Some safety reviews note gaps in data and environmental concerns, so we stay a bit cautious.

What to Do

Use products that are made for babies or toddlers and follow the product directions. Do a small patch test on a small area of the child’s skin before wider use. Avoid using products with this ingredient over the whole body every day, keep it off broken or irritated skin, and keep products away from the child’s mouth and eyes. If you prefer, choose products that list fewer additives or are labeled for infant/toddler use.

⚠️Warnings

Watch for redness, rash, itching, swelling or breathing trouble — stop use and contact your pediatrician if these happen. Note that a government review has raised concerns about environmental persistence and possible non-reproductive organ effects (Environment Canada). Industry reviewers also point out missing safety data and that some safety conclusions were based on related chemicals rather than direct studies (Cosmetic Ingredient Review, CIR). Also be aware that some product verification programs restrict use of this ingredient unless manufacturers provide safety data — if you see a restricted note on a product, consider choosing an alternative.

Confidence: MEDIUM

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Safety Risk Labels

This ingredient has the following documented risks:

Organ Risk: Environment Canada reviewed this ingredient and flagged it as likely to be toxic or harmful to non-reproductive organs and gave it a medium human-health priority. That means repeated or large exposures could harm organs like the liver or kidneys, according to that assessment.
Builds Up: Environment Canada identified this substance as persistent and potentially bioaccumulative with a moderate-to-high toxicity concern. Persistent and bioaccumulative substances can collect in the body over time with repeated use, which raises long‑term exposure worries.
Environmental: An environmental review found this ingredient is suspected to be an environmental toxin and raised ecotoxicology concerns. This means it may harm wildlife or persist in the environment after use.
Long-Term Risk: Because regulators have noted persistence, possible buildup, and organ toxicity potential, there is a plausible link to longer-term health effects from repeated exposure. The cosmetic safety review also notes data gaps, so long-term effects are not fully ruled out.

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Alternative Names for Poloxamer 407

This ingredient may also be listed as:

poloxamer 407UNII-52901V8XARPROPYLENE OXIDE ETHYLENE OXIDE75-H-1400OXIRANE, POLYMER WITH OXIRANE.ALPHA.-HYDRO-.OMEGA.-HYDROXYPOLY(OXYETHYLENE)POLY(OXYPROPYLENE)POLY(OXYETHYLENE) BLOCK COPOLYMERALPHA-HYDRO-OMEGA-HYDROXYPOLY(OXYETHYLENE)A-POLY(OXOPROPYLENE)B-POLY(OXYETHYLENE)A BLOCK COPOLYMERADEKA PLURONIC F-108ETHYLENE OXIDE PROPYLENE OXIDE199SZS8E2QTSL 431

Always check ingredient labels carefully, as ingredients may be listed under different names.

Common Questions About Poloxamer 407

Is this toddler-safe to use Poloxamer 407?

Yes, Poloxamer 407 is generally considered safe for 1-2 year old toddlers based on current research.

What are the organ risk risks of Poloxamer 407 for toddlers?

May harm organs like liver, kidneys, or lungs with repeated use. Young children may be more sensitive to these effects.

What are the builds up risks of Poloxamer 407 for toddlers?

Builds up in the body over time with repeated use. Young children may be more sensitive to these effects.

What are the environmental risks of Poloxamer 407 for toddlers?

Possible negative effects on the environment Young children may be more sensitive to these effects.

What are the long-term risk risks of Poloxamer 407 for toddlers?

Linked to long-term health effects after years of use or exposure. Young children may be more sensitive to these effects.

What products contain Poloxamer 407?

Poloxamer 407 is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.

When can toddlers using products with Poloxamer 407?

The appropriate age depends on the specific ingredient properties and concentration. This analysis is for 1-2 year old toddlers. Use the age selector above to check other ages.

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