Tetrasodium Glutamate Diacetate

Tetrasodium Glutamate Diacetate molecular structurePubChem

1-2 year old toddlers • Skin contact product

Check for Different Age (6 available)

Is this toddler-safe to use Tetrasodium Glutamate Diacetate?

✅
YES - Generally Safe
Danger Score: 2 (Lower is safer)
Quick Answer: Tetrasodium Glutamate Diacetate is generally considered safe for 1-2 year old toddlers when used in topical products. Watch for toddler-specific sensitivities.

ℹ️General Overview

For toddlers (1–2 year olds), this ingredient is commonly used to help products stay stable and is low risk at normal use levels. Most children will not have problems, but safety reviewers have raised concerns about possible contamination and a small chance of mild irritation.

✅What to Do

Use products made for children when possible and follow product directions. Avoid applying to broken or irritated skin. If you try a new product, put a small amount on a patch of your child’s skin (for example on the inner forearm) and watch for 24–48 hours for any redness or rash. Prefer brands that disclose safety testing or that state they test for impurities.

⚠️Warnings

Watch for skin redness, itching, or eye irritation and stop use if these occur. Safety reviews note possible contamination with other chemicals (for example nitrilotriacetic acid and related impurities) — this is the main concern flagged by reviewers (Cosmetic Ingredient Review and similar safety reviews). Some regulatory agencies also reported limited evidence of mild skin and eye irritation (European Chemicals Agency) and limited mutagenicity signals in one review (U.S. Environmental Protection Agency). Because there are data gaps, avoid using multiple leave-on products with this ingredient at once on young children and check product labels or manufacturer information if you have concerns.

Confidence: MEDIUM

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Safety Risk Labels

This ingredient has the following documented risks:

Cancer: A U.S. environmental agency reported limited evidence that this ingredient can act as a mutagen. Mutagen findings raise concern because they can be linked to cancer risk with repeated or high exposure.
Organ Risk: A cosmetic safety review noted animal studies that showed changes in organ weights for mothers and their offspring at high doses. That points to possible harm to organs with repeated or large exposures.
Fertility: The same cosmetic safety review found evidence from animal studies of effects on mothers and offspring at high doses, which suggests possible developmental or reproductive effects.
Irritant: A European chemical agency found limited evidence this ingredient can irritate skin and eyes, and the ingredient file also notes possible irritation to skin, eyes or lungs. This can cause redness, stinging or discomfort on sensitive baby skin.
Absorbed: The ingredient record flags enhanced skin absorption. That means it can get through the skin and into the body more easily, raising the chance that the other risks above could reach internal organs.
Long-Term Risk: The ingredient file flags high contamination concerns (including chemicals such as nitrilotriacetic-type impurities) and also notes data gaps in safety testing. Contamination plus incomplete safety data raise concern for possible long-term health effects if exposure is repeated.

Tap or hover over labels to see detailed risk information.

Alternative Names for Tetrasodium Glutamate Diacetate

This ingredient may also be listed as:

tetrasodium glutamate diacetateTETRASODIUM GLUTAMATE DIACETATEL-GLUTAMIC ACID, N,N-BIS(CARBOXYMETHYL)-, TETRASODIUM SALTTETRASODIUM SALT L-GLUTAMIC ACID, N,N-BIS(CARBOXYMETHYL)-N,N-BIS(CARBOXYMETHYL)- TETRASODIUM SALT L-GLUTAMIC ACIDTETRASODIUM N,N-BIS(CARBOXYLATOMETHYL)-L-GLUTAMATE2-BIS(SODIOOXYCARBONYLMETHYL)AMINOGLUTARIC ACID DISODIUM SALT

Always check ingredient labels carefully, as ingredients may be listed under different names.

Products Containing Tetrasodium Glutamate Diacetate

This ingredient is found in the following products:

This list shows products that contain Tetrasodium Glutamate Diacetate or its alternative names.

Common Questions About Tetrasodium Glutamate Diacetate

Is this toddler-safe to use Tetrasodium Glutamate Diacetate?

Yes, Tetrasodium Glutamate Diacetate is generally considered safe for 1-2 year old toddlers based on current research.

What are the cancer risks of Tetrasodium Glutamate Diacetate for toddlers?

Connected to cancer risk with long-term or repeated exposure. Young children may be more sensitive to these effects.

What are the organ risk risks of Tetrasodium Glutamate Diacetate for toddlers?

May harm organs like liver, kidneys, or lungs with repeated use. Young children may be more sensitive to these effects.

What are the fertility risks of Tetrasodium Glutamate Diacetate for toddlers?

Some studies link this to future fertility or reproductive issues. Young children may be more sensitive to these effects.

What are the irritant risks of Tetrasodium Glutamate Diacetate for toddlers?

Can cause skin redness, itchiness, or rashes—especially on sensitive baby skin. Young children may be more sensitive to these effects.

What are the absorbed risks of Tetrasodium Glutamate Diacetate for toddlers?

Can be absorbed through the skin and get into the bloodstream. Young children may be more sensitive to these effects.

What are the long-term risk risks of Tetrasodium Glutamate Diacetate for toddlers?

Linked to long-term health effects after years of use or exposure. Young children may be more sensitive to these effects.

What products contain Tetrasodium Glutamate Diacetate?

Tetrasodium Glutamate Diacetate is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.

When can toddlers using products with Tetrasodium Glutamate Diacetate?

The appropriate age depends on the specific ingredient properties and concentration. This analysis is for 1-2 year old toddlers. Use the age selector above to check other ages.

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