Poloxamer 407

2-5 year old preschoolersSkin contact product

Check for Different Age (6 available)

Safe for preschoolers to use Poloxamer 407?

YES - Generally Safe
Danger Score: 1 (Lower is safer)
Quick Answer: Poloxamer 407 is generally considered safe for 2-5 year old children when used in topical products. Consider preschooler activity levels.

ℹ️General Overview

For toddlers and preschoolers (ages 2–5), this ingredient used in small amounts in wipes, shampoos, and lotions is generally low risk and unlikely to cause problems for most children.

What to Do

Use products that list this ingredient in normal baby or children’s skin and hair products. Do a small patch test on the arm before using a new product on a child. Avoid applying products with this ingredient to open cuts, raw or irritated areas, and keep them away from the eyes and mouth. Stop use and rinse if you see redness, rash, or irritation and talk to your child’s doctor if it continues.

⚠️Warnings

Some government reviews have raised concerns about environmental persistence and possible effects on organs (source: Environment Canada). Industry safety reviewers have also noted missing safety data and that some safety conclusions were based on related chemicals rather than direct tests (source: Cosmetic Ingredient Review). Because of those notes, avoid heavy or long-term use on young children, avoid use on broken skin, and watch for any skin reactions. If your child has eczema, very sensitive skin, or if the product will be used over large areas for a long time, check with your pediatrician first.

Confidence: MEDIUM

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Safety Risk Labels

This ingredient has the following documented risks:

Organ Risk: Environment Canada reviewed this ingredient and flagged it as likely to be toxic or harmful to non-reproductive organs and gave it a medium human-health priority. That means repeated or large exposures could harm organs like the liver or kidneys, according to that assessment.
Builds Up: Environment Canada identified this substance as persistent and potentially bioaccumulative with a moderate-to-high toxicity concern. Persistent and bioaccumulative substances can collect in the body over time with repeated use, which raises long‑term exposure worries.
Environmental: An environmental review found this ingredient is suspected to be an environmental toxin and raised ecotoxicology concerns. This means it may harm wildlife or persist in the environment after use.
Long-Term Risk: Because regulators have noted persistence, possible buildup, and organ toxicity potential, there is a plausible link to longer-term health effects from repeated exposure. The cosmetic safety review also notes data gaps, so long-term effects are not fully ruled out.

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Alternative Names for Poloxamer 407

This ingredient may also be listed as:

poloxamer 407UNII-52901V8XARPROPYLENE OXIDE ETHYLENE OXIDE75-H-1400OXIRANE, POLYMER WITH OXIRANE.ALPHA.-HYDRO-.OMEGA.-HYDROXYPOLY(OXYETHYLENE)POLY(OXYPROPYLENE)POLY(OXYETHYLENE) BLOCK COPOLYMERALPHA-HYDRO-OMEGA-HYDROXYPOLY(OXYETHYLENE)A-POLY(OXOPROPYLENE)B-POLY(OXYETHYLENE)A BLOCK COPOLYMERADEKA PLURONIC F-108ETHYLENE OXIDE PROPYLENE OXIDE199SZS8E2QTSL 431

Always check ingredient labels carefully, as ingredients may be listed under different names.

Common Questions About Poloxamer 407

Safe for preschoolers to use Poloxamer 407?

Yes, Poloxamer 407 is generally considered safe for 2-5 year old children based on current research.

What are the organ risk risks of Poloxamer 407 for preschoolers?

May harm organs like liver, kidneys, or lungs with repeated use. Young children may be more sensitive to these effects.

What are the builds up risks of Poloxamer 407 for preschoolers?

Builds up in the body over time with repeated use. Young children may be more sensitive to these effects.

What are the environmental risks of Poloxamer 407 for preschoolers?

Possible negative effects on the environment Young children may be more sensitive to these effects.

What are the long-term risk risks of Poloxamer 407 for preschoolers?

Linked to long-term health effects after years of use or exposure. Young children may be more sensitive to these effects.

What products contain Poloxamer 407?

Poloxamer 407 is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.

Is this suitable for preschoolers to using products with Poloxamer 407?

The appropriate age depends on the specific ingredient properties and concentration. This analysis is for 2-5 year old children. Use the age selector above to check other ages.

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