For toddlers and preschoolers (2–5 years), propylene glycol in typical skin creams is usually low risk, but it can cause skin irritation or allergic reactions in some children. It can also help other ingredients get into the skin, so be careful with strong medicines in the same product.
Use products that list propylene glycol at low concentrations and are made for children or labeled gentle/fragrance-free. Do a small patch test (apply a little on the inner forearm) and wait 24 hours to check for redness or itching. Don’t use it on broken, red, or sore skin. If you plan to use a product containing strong active ingredients (like prescription medicines) or put it over large areas every day, check with your child’s doctor first.
Watch for redness, itching, swelling, blistering, or any new rash after use — stop the product and see a doctor if these occur (skin irritation warning from the U.S. National Library of Medicine). Be careful because it can increase skin absorption of other ingredients (noted by the Cosmetic Ingredient Review). Some reviews flagged possible non-reproductive organ toxicity concerns (Environment Canada) and recommend following product concentration limits (Cosmetic Ingredient Review / FDA guidance).
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Scientific research related to this ingredient:
These research articles provide scientific evidence about Propylene Glycol safety and effects.
Yes, Propylene Glycol is generally considered safe for 2-5 year old children based on current research.
Can cause skin redness, itchiness, or rashes—especially on sensitive baby skin. Young children may be more sensitive to these effects.
Could weaken or confuse immune system. Young children may be more sensitive to these effects.
May harm organs like liver, kidneys, or lungs with repeated use. Young children may be more sensitive to these effects.
Can be absorbed through the skin and get into the bloodstream. Young children may be more sensitive to these effects.
Can make breathing issues like asthma worse in babies and kids. Young children may be more sensitive to these effects.
Propylene Glycol is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.
The appropriate age depends on the specific ingredient properties and concentration. This analysis is for 2-5 year old children. Use the age selector above to check other ages.
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