2-5 year old preschoolers • Skin contact product
For toddlers and young children (2–5 years), protease is usually low risk for things like cancer or long-term development, but it can cause allergic reactions in some people. That makes it something to be careful with around young children.
If you see a product that lists protease, choose products made for children when possible. Do a small patch test on a clean area (inner forearm) and wait 24 hours before using more widely. Don’t use products with protease on broken, red, or very dry/eczema-prone skin. Stop use right away and wash the area if you see redness, swelling, or itching, and call your pediatrician if it is severe.
Studies in scientific journals show protease can be a human allergen — so watch for rash, itching, swelling, or breathing problems. A cosmetics safety database also notes that this ingredient is restricted in some verified product programs unless safety is proven. Additionally, the U.S. food authority recognizes protease as safe for limited food uses, but that does not remove the risk of skin allergy. If your child has eczema, asthma, or many known allergies, avoid protease-containing products unless a doctor approves.
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Use caution with Protease for 2-5 year old children. Some safety concerns have been identified.
Could weaken or confuse immune system. Young children may be more sensitive to these effects.
Can cause skin redness, itchiness, or rashes—especially on sensitive baby skin. Young children may be more sensitive to these effects.
Linked to triggering or worsening eczema and similar skin conditions. Young children may be more sensitive to these effects.
Protease is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.
The appropriate age depends on the specific ingredient properties and concentration. This analysis is for 2-5 year old children. Use the age selector above to check other ages.
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