Symphytum Officinale Extract

Symphytum Officinale Extract molecular structure

2-5 year old preschoolersSkin contact product

Check for Different Age (6 available)

Safe for preschoolers to use Symphytum Officinale Extract?

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NOT RECOMMENDED
Danger Score: 6 (Lower is safer)
Quick Answer: Symphytum Officinale Extract not recommended for 2-5 year old children when used in topical products. Consider preschooler activity levels.

ℹ️General Overview

For toddlers and preschoolers (2–5 years), comfrey extract is best avoided. It can carry liver-damaging chemicals and has been linked to serious liver injury in people and to cancer in animals.

What to Do

Avoid products that list comfrey, Symphytum officinale, or any of its synonyms on the label for children aged 2–5. If you accidentally use a product with comfrey on your child, wash the area, don’t apply it to broken or irritated skin, use it only briefly on a very small area, and call your pediatrician if you notice a rash or any signs of illness. Always check ingredient lists and ask your child’s clinician if you’re unsure.

⚠️Warnings

Do not use on broken skin or large skin areas of young children. Watch for skin redness, swelling, persistent stomach pain, dark urine, yellowing of the skin or eyes, or extreme tiredness — these can be signs of liver damage reported in medical case reports and regulator advisories (for example, public health advice that recommended removing some comfrey products from the market). Studies in animals have also shown tumor formation after comfrey exposure. The main concern source is contamination with pyrrolizidine alkaloids and published medical/regulatory reports linking comfrey to liver injury.

Confidence: HIGH

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Safety Risk Labels

This ingredient has the following documented risks:

Cancer: Animal studies found tumors after exposure and lab tests show the plant extract can cause mutations in mammal cells. A national food safety agency has warned that comfrey may be a possible human carcinogen, so there is a real cancer risk with repeated or high exposure.
Organ Risk: There are multiple human case reports linking comfrey use to serious liver injury (hepatic veno‑occlusive disease). A national regulatory health agency has flagged comfrey as a known liver toxicant, so it can harm the liver with use.
Absorbed: The ingredient has been flagged for enhanced skin absorption and can carry harmful pyrrolizidine alkaloids into the body through the skin. That means the toxic chemicals can get into the bloodstream even when used topically.
Banned: A major food and drug safety agency advised manufacturers to remove comfrey products from the market because of safety concerns, and some product verification programs restrict its use. This shows it is restricted or removed in some regulatory settings.
Long-Term Risk: Because of documented liver damage in people and tumor formation in animals, repeated or long-term use raises the chance of serious health problems over time. Studies and regulatory actions point to lasting risk with ongoing exposure.

Tap or hover over labels to see detailed risk information.

Alternative Names for Symphytum Officinale Extract

This ingredient may also be listed as:

symphytum officinale extractSYMPHYTUM OFFICINALE EXTRACTSYMPHYTUM OFFICINALE (COMFREY) EXTRACTSYMPHYTUM OFFICINALIS EXTRACTEXTRACT OF SYMPHYTUM OFFICINALEEXTRACT OF COMFREYCOMFREY (SYMPHYTUM OFFICINALE) EXTRACTCOMFREY EXTRACT

Always check ingredient labels carefully, as ingredients may be listed under different names.

Common Questions About Symphytum Officinale Extract

Safe for preschoolers to use Symphytum Officinale Extract?

Symphytum Officinale Extract is not recommended for 2-5 year old children due to potential safety risks.

What are the cancer risks of Symphytum Officinale Extract for preschoolers?

Connected to cancer risk with long-term or repeated exposure. Young children may be more sensitive to these effects.

What are the organ risk risks of Symphytum Officinale Extract for preschoolers?

May harm organs like liver, kidneys, or lungs with repeated use. Young children may be more sensitive to these effects.

What are the absorbed risks of Symphytum Officinale Extract for preschoolers?

Can be absorbed through the skin and get into the bloodstream. Young children may be more sensitive to these effects.

What are the banned risks of Symphytum Officinale Extract for preschoolers?

Banned or heavily restricted in one or more countries. Young children may be more sensitive to these effects.

What are the long-term risk risks of Symphytum Officinale Extract for preschoolers?

Linked to long-term health effects after years of use or exposure. Young children may be more sensitive to these effects.

What products contain Symphytum Officinale Extract?

Symphytum Officinale Extract is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.

Is this suitable for preschoolers to using products with Symphytum Officinale Extract?

The appropriate age depends on the specific ingredient properties and concentration. This analysis is for 2-5 year old children. Use the age selector above to check other ages.

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