Trisodium Ethylenediamine Disuccinate

2-5 year old preschoolersSkin contact product

Check for Different Age (6 available)

Safe for preschoolers to use Trisodium Ethylenediamine Disuccinate?

YES - Generally Safe
Danger Score: 1 (Lower is safer)
Quick Answer: Trisodium Ethylenediamine Disuccinate is generally considered safe for 2-5 year old children when used in topical products. Consider preschooler activity levels.

ℹ️General Overview

For toddlers and preschoolers (2-5 years), this ingredient is usually low risk in normal, low-strength skincare or rinse-off products. It isn’t commonly linked to serious problems in everyday use, but some scientific studies show it can make skin absorb more and can irritate eyes or skin at high doses.

What to Do

Use products that are made for children or labeled gentle. For this age group, prefer rinse-off products (like shampoos and washes) or leave-on products that list low concentrations and are formulated for kids. Do a small patch test on the arm before first use. Avoid applying near the eyes, mouth, or broken skin. If your child has sensitive skin, eczema, or will be using multiple active products, check with your pediatrician.

⚠️Warnings

Watch for redness, stinging, swelling, or eye irritation after use — stop use if any appear. The caution comes from peer-reviewed scientific studies that reported increased skin penetration and skin/eye irritation in animals at moderate to high doses, and some cell studies that showed mutation signals under lab conditions. These findings were at high exposures not typical of normal baby products, but they are why we recommend limiting heavy or repeated application and avoiding use near the eyes or broken skin.

Confidence: MEDIUM

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Safety Risk Labels

This ingredient has the following documented risks:

Absorbed: Peer‑reviewed studies identify this chemical as a penetration enhancer. That means it can help other ingredients pass through the skin and enter the bloodstream, which raises how much a child can absorb from a product.
Irritant: Animal studies in the peer‑reviewed literature show eye irritation at high doses and skin irritation at moderate doses. On sensitive baby skin this could cause redness, stinging, or a rash.
Cancer: Lab tests on mammal cells reported mutation‑positive results in peer‑reviewed work. That finding raises a possible cancer concern, though it comes from cell studies rather than human tests.
Organ Risk: Peer‑reviewed animal studies found effects on the pancreas at high doses. This shows the ingredient can harm internal organs under strong or repeated exposure in those studies.
Fertility: Peer‑reviewed animal studies report developmental or reproductive effects at high doses. That suggests a possible risk to development or future fertility with large or repeated exposures in those tests.
Long-Term Risk: Taken together, cell tests showing mutations and animal studies showing organ and reproductive effects (all from peer‑reviewed sources) point to possible long‑term health concerns if exposure is repeated over time.

Tap or hover over labels to see detailed risk information.

Alternative Names for Trisodium Ethylenediamine Disuccinate

This ingredient may also be listed as:

trisodium ethylenediamine disuccinateSODIUM SALT ETHYLENEDIAMINE DISUCCINATEETHYLENEDIAMINE-N,N'-DISUCCINIC ACIDETHYLENEDIAMINEDISUCCINIC ACIDSCHEMBL39257ETHYLENEBISIMINODISUCCINIC ACIDQ412231N-{2-[(1,2-DICARBOXYETHYL)AMINO]ETHYL}ASPARTIC ACID2-[2-(1,2-DICARBOXYETHYLAMINO)ETHYLAMINO]BUTANEDIOIC ACIDEDDSTRISODIUM ETHYLENEDIAMINE DISUCCINATEtrisodium ethylene diamine disuccinatetriosodium ethylenediamine disuccinateTRESODIUM ETHYLENEDIAMINE DISUCCINATE

Always check ingredient labels carefully, as ingredients may be listed under different names.

Products Containing Trisodium Ethylenediamine Disuccinate

This ingredient is found in the following products:

This list shows products that contain Trisodium Ethylenediamine Disuccinate or its alternative names.

Common Questions About Trisodium Ethylenediamine Disuccinate

Safe for preschoolers to use Trisodium Ethylenediamine Disuccinate?

Yes, Trisodium Ethylenediamine Disuccinate is generally considered safe for 2-5 year old children based on current research.

What are the absorbed risks of Trisodium Ethylenediamine Disuccinate for preschoolers?

Can be absorbed through the skin and get into the bloodstream. Young children may be more sensitive to these effects.

What are the irritant risks of Trisodium Ethylenediamine Disuccinate for preschoolers?

Can cause skin redness, itchiness, or rashes—especially on sensitive baby skin. Young children may be more sensitive to these effects.

What are the cancer risks of Trisodium Ethylenediamine Disuccinate for preschoolers?

Connected to cancer risk with long-term or repeated exposure. Young children may be more sensitive to these effects.

What are the organ risk risks of Trisodium Ethylenediamine Disuccinate for preschoolers?

May harm organs like liver, kidneys, or lungs with repeated use. Young children may be more sensitive to these effects.

What are the fertility risks of Trisodium Ethylenediamine Disuccinate for preschoolers?

Some studies link this to future fertility or reproductive issues. Young children may be more sensitive to these effects.

What are the long-term risk risks of Trisodium Ethylenediamine Disuccinate for preschoolers?

Linked to long-term health effects after years of use or exposure. Young children may be more sensitive to these effects.

What products contain Trisodium Ethylenediamine Disuccinate?

Trisodium Ethylenediamine Disuccinate is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.

Is this suitable for preschoolers to using products with Trisodium Ethylenediamine Disuccinate?

The appropriate age depends on the specific ingredient properties and concentration. This analysis is for 2-5 year old children. Use the age selector above to check other ages.

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