Poloxamer 407

5+ year old childrenSkin contact product

Check for Different Age (6 available)

Is this kid-friendly to use Poloxamer 407?

YES - Generally Safe
Danger Score: 1 (Lower is safer)
Quick Answer: Poloxamer 407 is generally considered safe for 5+ year old children when used in topical products. Kids may have different tolerance levels.

ℹ️General Overview

For children 5 years and older (kids, school-age children, preteens), poloxamer 407 used on the skin is usually low risk. It’s a mild cleaning ingredient used in wipes, shampoos and lotions and rarely causes problems at the amounts normally used.

What to Do

Pick products made for children or everyday use and follow the product directions. Don’t put products containing this ingredient on open cuts or very red, broken skin. If your child has sensitive skin, do a small patch test on the arm first. If any rash, redness, swelling or breathing trouble happens, stop use and seek medical help.

⚠️Warnings

Some government and industry reviews (for example Environment Canada and the Cosmetic Ingredient Review) note limited safety data, possible concerns about environmental persistence, and some non-reproductive organ toxicity findings — these are the reasons to be cautious even though direct skin risks for kids are low. Also note that some product verification programs restrict use of this ingredient unless manufacturers provide safety data. Watch for signs of local skin reaction (redness, itching, rash), eye irritation if used near the eyes, and any unusual symptoms after use; if those appear, stop use and consult your child’s clinician.

Confidence: MEDIUM

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Safety Risk Labels

This ingredient has the following documented risks:

Organ Risk: Environment Canada reviewed this ingredient and flagged it as likely to be toxic or harmful to non-reproductive organs and gave it a medium human-health priority. That means repeated or large exposures could harm organs like the liver or kidneys, according to that assessment.
Builds Up: Environment Canada identified this substance as persistent and potentially bioaccumulative with a moderate-to-high toxicity concern. Persistent and bioaccumulative substances can collect in the body over time with repeated use, which raises long‑term exposure worries.
Environmental: An environmental review found this ingredient is suspected to be an environmental toxin and raised ecotoxicology concerns. This means it may harm wildlife or persist in the environment after use.
Long-Term Risk: Because regulators have noted persistence, possible buildup, and organ toxicity potential, there is a plausible link to longer-term health effects from repeated exposure. The cosmetic safety review also notes data gaps, so long-term effects are not fully ruled out.

Tap or hover over labels to see detailed risk information.

Alternative Names for Poloxamer 407

This ingredient may also be listed as:

poloxamer 407UNII-52901V8XARPROPYLENE OXIDE ETHYLENE OXIDE75-H-1400OXIRANE, POLYMER WITH OXIRANE.ALPHA.-HYDRO-.OMEGA.-HYDROXYPOLY(OXYETHYLENE)POLY(OXYPROPYLENE)POLY(OXYETHYLENE) BLOCK COPOLYMERALPHA-HYDRO-OMEGA-HYDROXYPOLY(OXYETHYLENE)A-POLY(OXOPROPYLENE)B-POLY(OXYETHYLENE)A BLOCK COPOLYMERADEKA PLURONIC F-108ETHYLENE OXIDE PROPYLENE OXIDE199SZS8E2QTSL 431

Always check ingredient labels carefully, as ingredients may be listed under different names.

Common Questions About Poloxamer 407

Is this kid-friendly to use Poloxamer 407?

Yes, Poloxamer 407 is generally considered safe for 5+ year old children based on current research.

What are the organ risk risks of Poloxamer 407 for children?

May harm organs like liver, kidneys, or lungs with repeated use.

What are the builds up risks of Poloxamer 407 for children?

Builds up in the body over time with repeated use.

What are the environmental risks of Poloxamer 407 for children?

Possible negative effects on the environment

What are the long-term risk risks of Poloxamer 407 for children?

Linked to long-term health effects after years of use or exposure.

What products contain Poloxamer 407?

Poloxamer 407 is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.

When can kids start using products with Poloxamer 407?

The appropriate age depends on the specific ingredient properties and concentration. This analysis is for 5+ year old children. Use the age selector above to check other ages.

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