Protease

Protease molecular structure

5+ year old children • Skin contact product

Check for Different Age (6 available)

Is this kid-friendly to use Protease?

✅
YES - Generally Safe
Danger Score: 3 (Lower is safer)
Quick Answer: Protease is generally considered safe for 5+ year old children when used in topical products. Kids may have different tolerance levels.

ℹ️General Overview

For children aged 5 and up (school-age kids), protease is usually low risk but can cause skin allergies in some children. It is safer for this age than for babies and toddlers, but still not risk-free.

✅What to Do

Before using a product with protease on your child, do a patch test: put a tiny amount on the inside of the forearm and wait 24–48 hours. Use a small amount at first, avoid the face and any cuts or sore skin, and only use products made for children when possible. If your child has a history of skin allergies or asthma, talk to your pediatrician before using products with this ingredient.

⚠️Warnings

Watch for redness, itching, swelling, hives, or any breathing trouble. Peer-reviewed studies show protease can act as an allergen, and some product standards restrict its use without extra safety proof. Also avoid inhaling powders or sprays that contain enzymes. If you see a severe reaction, get medical help right away.

Confidence: HIGH

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Safety Risk Labels

This ingredient has the following documented risks:

Immune system: Peer-reviewed studies show this protease acts as a human allergen and can trigger immune reactions. That means some people — including children with sensitive skin — could have allergic responses after using products that contain it.
Irritant: Because the ingredient can cause allergic reactions in people, it can also lead to skin redness, itching, or rashes when applied to the skin. This risk is supported by peer-reviewed literature reporting strong evidence of human allergen effects.
Eczema: Allergic or immune reactions to this protease can trigger or make eczema and similar skin conditions worse. Peer-reviewed sources note strong allergen evidence, which makes flare-ups more likely for children with eczema-prone skin.

Tap or hover over labels to see detailed risk information.

Alternative Names for Protease

This ingredient may also be listed as:

proteasePROTEASEBACILLUS SUBTILIS NEUTRAL PROTEASEA.S. 1.398BACTERIAL PROTEASE

Always check ingredient labels carefully, as ingredients may be listed under different names.

Common Questions About Protease

Is this kid-friendly to use Protease?

Yes, Protease is generally considered safe for 5+ year old children based on current research.

What are the immune system risks of Protease for children?

Could weaken or confuse immune system.

What are the irritant risks of Protease for children?

Can cause skin redness, itchiness, or rashes—especially on sensitive baby skin.

What are the eczema risks of Protease for children?

Linked to triggering or worsening eczema and similar skin conditions.

What products contain Protease?

Protease is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.

When can kids start using products with Protease?

The appropriate age depends on the specific ingredient properties and concentration. This analysis is for 5+ year old children. Use the age selector above to check other ages.

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