For children 5 years and older (school-age kids), this ingredient is usually low risk when used in normal skin care or personal care products. It helps keep formulas stable. Most safety reviews find little concern, but some scientific studies show it can make skin absorb other substances more easily and can irritate eyes or skin at higher doses.
Use products that include this ingredient as directed and in amounts made for regular skin care. Do not put products with this ingredient on broken, red, or irritated skin. Avoid getting the product in your child’s eyes or mouth. If your child has sensitive skin, do a small patch test on the arm first. If your child develops redness, itching, swelling, or any unusual reaction, stop use and rinse the area, and talk with your pediatrician.
Peer-reviewed studies note three things to watch for: (1) it can act as a penetration enhancer (may increase how much other ingredients get through the skin); (2) animal studies showed eye irritation at high doses and skin irritation at moderate doses; and (3) some high-dose animal tests showed organ or developmental effects, and some cell tests showed mutation signals. Because of these findings from peer-reviewed literature, avoid use near the eyes, avoid on broken skin, and discontinue if irritation occurs. If you are using a leave-on product on a child under 5 years old, check with your pediatrician first.
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This ingredient has the following documented risks:
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This ingredient may also be listed as:
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This ingredient is found in the following products:
This list shows products that contain Trisodium Ethylenediamine Disuccinate or its alternative names.
Yes, Trisodium Ethylenediamine Disuccinate is generally considered safe for 5+ year old children based on current research.
Can be absorbed through the skin and get into the bloodstream.
Can cause skin redness, itchiness, or rashes—especially on sensitive baby skin.
Connected to cancer risk with long-term or repeated exposure.
May harm organs like liver, kidneys, or lungs with repeated use.
Some studies link this to future fertility or reproductive issues.
Linked to long-term health effects after years of use or exposure.
Trisodium Ethylenediamine Disuccinate is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.
The appropriate age depends on the specific ingredient properties and concentration. This analysis is for 5+ year old children. Use the age selector above to check other ages.
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