Trisodium Ethylenediamine Disuccinate

5+ year old childrenSkin contact product

Check for Different Age (6 available)

Is this kid-friendly to use Trisodium Ethylenediamine Disuccinate?

YES - Generally Safe
Danger Score: 1 (Lower is safer)
Quick Answer: Trisodium Ethylenediamine Disuccinate is generally considered safe for 5+ year old children when used in topical products. Kids may have different tolerance levels.

ℹ️General Overview

For children 5 years and older (school-age kids), this ingredient is usually low risk when used in normal skin care or personal care products. It helps keep formulas stable. Most safety reviews find little concern, but some scientific studies show it can make skin absorb other substances more easily and can irritate eyes or skin at higher doses.

What to Do

Use products that include this ingredient as directed and in amounts made for regular skin care. Do not put products with this ingredient on broken, red, or irritated skin. Avoid getting the product in your child’s eyes or mouth. If your child has sensitive skin, do a small patch test on the arm first. If your child develops redness, itching, swelling, or any unusual reaction, stop use and rinse the area, and talk with your pediatrician.

⚠️Warnings

Peer-reviewed studies note three things to watch for: (1) it can act as a penetration enhancer (may increase how much other ingredients get through the skin); (2) animal studies showed eye irritation at high doses and skin irritation at moderate doses; and (3) some high-dose animal tests showed organ or developmental effects, and some cell tests showed mutation signals. Because of these findings from peer-reviewed literature, avoid use near the eyes, avoid on broken skin, and discontinue if irritation occurs. If you are using a leave-on product on a child under 5 years old, check with your pediatrician first.

Confidence: HIGH

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Safety Risk Labels

This ingredient has the following documented risks:

Absorbed: Peer‑reviewed studies identify this chemical as a penetration enhancer. That means it can help other ingredients pass through the skin and enter the bloodstream, which raises how much a child can absorb from a product.
Irritant: Animal studies in the peer‑reviewed literature show eye irritation at high doses and skin irritation at moderate doses. On sensitive baby skin this could cause redness, stinging, or a rash.
Cancer: Lab tests on mammal cells reported mutation‑positive results in peer‑reviewed work. That finding raises a possible cancer concern, though it comes from cell studies rather than human tests.
Organ Risk: Peer‑reviewed animal studies found effects on the pancreas at high doses. This shows the ingredient can harm internal organs under strong or repeated exposure in those studies.
Fertility: Peer‑reviewed animal studies report developmental or reproductive effects at high doses. That suggests a possible risk to development or future fertility with large or repeated exposures in those tests.
Long-Term Risk: Taken together, cell tests showing mutations and animal studies showing organ and reproductive effects (all from peer‑reviewed sources) point to possible long‑term health concerns if exposure is repeated over time.

Tap or hover over labels to see detailed risk information.

Alternative Names for Trisodium Ethylenediamine Disuccinate

This ingredient may also be listed as:

trisodium ethylenediamine disuccinateSODIUM SALT ETHYLENEDIAMINE DISUCCINATEETHYLENEDIAMINE-N,N'-DISUCCINIC ACIDETHYLENEDIAMINEDISUCCINIC ACIDSCHEMBL39257ETHYLENEBISIMINODISUCCINIC ACIDQ412231N-{2-[(1,2-DICARBOXYETHYL)AMINO]ETHYL}ASPARTIC ACID2-[2-(1,2-DICARBOXYETHYLAMINO)ETHYLAMINO]BUTANEDIOIC ACIDEDDSTRISODIUM ETHYLENEDIAMINE DISUCCINATEtrisodium ethylene diamine disuccinatetriosodium ethylenediamine disuccinateTRESODIUM ETHYLENEDIAMINE DISUCCINATE

Always check ingredient labels carefully, as ingredients may be listed under different names.

Products Containing Trisodium Ethylenediamine Disuccinate

This ingredient is found in the following products:

This list shows products that contain Trisodium Ethylenediamine Disuccinate or its alternative names.

Common Questions About Trisodium Ethylenediamine Disuccinate

Is this kid-friendly to use Trisodium Ethylenediamine Disuccinate?

Yes, Trisodium Ethylenediamine Disuccinate is generally considered safe for 5+ year old children based on current research.

What are the absorbed risks of Trisodium Ethylenediamine Disuccinate for children?

Can be absorbed through the skin and get into the bloodstream.

What are the irritant risks of Trisodium Ethylenediamine Disuccinate for children?

Can cause skin redness, itchiness, or rashes—especially on sensitive baby skin.

What are the cancer risks of Trisodium Ethylenediamine Disuccinate for children?

Connected to cancer risk with long-term or repeated exposure.

What are the organ risk risks of Trisodium Ethylenediamine Disuccinate for children?

May harm organs like liver, kidneys, or lungs with repeated use.

What are the fertility risks of Trisodium Ethylenediamine Disuccinate for children?

Some studies link this to future fertility or reproductive issues.

What are the long-term risk risks of Trisodium Ethylenediamine Disuccinate for children?

Linked to long-term health effects after years of use or exposure.

What products contain Trisodium Ethylenediamine Disuccinate?

Trisodium Ethylenediamine Disuccinate is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.

When can kids start using products with Trisodium Ethylenediamine Disuccinate?

The appropriate age depends on the specific ingredient properties and concentration. This analysis is for 5+ year old children. Use the age selector above to check other ages.

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