For babies 6–12 months (older infants), this dye is a moderate concern. It is a synthetic color used in cosmetics and can sometimes irritate skin or eyes. There are also official-use limits and some evidence that it can build up in the environment or affect hormones, so it’s safer to avoid it on baby skin when you can.
If possible, choose baby products that do not list CI 45410 (D&C Red No. 27/28). If you must use a product that contains it: 1) don’t use it near your baby’s eyes or on broken or irritated skin, 2) do a small patch test on a tiny area of the baby’s thigh or behind the ear and wait 24–48 hours for any reaction, 3) use products made/formulated for infants at low concentration, and 4) stop use and wash the area if you see redness, swelling, blistering, or any change in behavior (excessive fussiness, poor feeding). Talk with your pediatrician if you’re unsure or if a reaction occurs.
Things to avoid and watch for: 1) Avoid getting products with this dye in the eyes — the U.S. food authority does not approve it for eye-area cosmetics. 2) Watch for skin redness, rash, swelling, or eye irritation — some animal and agency reviews report irritation at higher doses. 3) Consider that there are official restrictions on how it may be used in cosmetics; follow product instructions and avoid hair-dye or eye-makeup types for babies. 4) Note that some agencies flag possible hormone-related effects and environmental persistence — these are listed as concerns by regulatory and scientific bodies (for example, reviews and opinions from food safety agencies, national toxicology programs, and environmental agencies).
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CI 45410 is not recommended for 6-12 month old babies due to potential safety risks.
Banned or heavily restricted in one or more countries. This is especially important for babies whose skin and systems are still developing.
Builds up in the body over time with repeated use. This is especially important for babies whose skin and systems are still developing.
Linked to PFAS or similar chemicals that stay in the body and environment for years, potentially causing long-term harm. This is especially important for babies whose skin and systems are still developing.
May harm organs like liver, kidneys, or lungs with repeated use. This is especially important for babies whose skin and systems are still developing.
Can be absorbed through the skin and get into the bloodstream. This is especially important for babies whose skin and systems are still developing.
CI 45410 is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.
The appropriate age depends on the specific ingredient properties and concentration. This analysis is for 6-12 month old babies. Use the age selector above to check other ages.
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