For adults and teens: this preservative can cause skin allergies in some people. It is allowed in some products but is restricted or banned for leave-on use in several countries. Rinse-off products (like shampoos or body washes) usually carry less risk than leave-on products.
If you have sensitive skin or a known preservative allergy, avoid products that list Methylchloroisothiazolinone (also seen as MI/CMI or Kathon). For new products, try a small patch on your inner arm and wait 24–48 hours before regular use. Prefer rinse-off formulations if you choose a product containing it. Stop use right away if you get redness, itching, or a rash.
Do not use products with this ingredient on irritated or broken skin. Regulators and safety review panels (for example Health Canada and cosmetic safety reviews) have restricted or banned its use in some products because of allergic reactions. Watch for signs of an allergic reaction—redness, itching, blistering, or swelling—and seek medical advice if these occur. Published case reports, including reactions from wet wipes, show that contact allergy can happen after repeated or prolonged exposure.
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This ingredient has the following documented risks:
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This ingredient may also be listed as:
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This ingredient is found in the following products:
This list shows products that contain Methylchloroisothiazolinone or its alternative names.
Scientific research related to this ingredient:
These research articles provide scientific evidence about Methylchloroisothiazolinone safety and effects.
Use caution with Methylchloroisothiazolinone for adults. Some safety concerns have been identified.
Could weaken or confuse immune system.
Linked to triggering or worsening eczema and similar skin conditions.
Can cause skin redness, itchiness, or rashes—especially on sensitive baby skin.
Banned or heavily restricted in one or more countries.
Can be absorbed through the skin and get into the bloodstream.
Builds up in the body over time with repeated use.
Methylchloroisothiazolinone is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.
The appropriate age depends on the specific ingredient properties and concentration. This analysis is for adults. Use the age selector above to check other ages.
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