For adults, Poloxamer 188 is very low risk when used in creams, gels or cleansers at normal concentrations. It is commonly used and not linked to major health problems in adults.
Use products as directed. If you have sensitive skin, do a small patch test before widespread use. Avoid applying to broken or irritated skin. If you are pregnant, breastfeeding, or have a serious health condition, check with your healthcare provider. Prefer products from reputable brands that list ingredients clearly and follow concentration guidance from safety reviews.
Watch for skin irritation or allergic reaction (industry safety reviews/Cosmetic Ingredient Review). Some reviews note data gaps and that safety depends on concentration and product type (Cosmetic Ingredient Review). Government assessments flagged possible environmental persistence and potential for non-reproductive organ toxicity (Environment Canada). Also note it is used in some food applications, so there can be multiple sources of exposure (U.S. FDA). Avoid using large amounts or using frequently on broken skin, and stop use and consult a doctor if you develop redness, severe itch, swelling, or other concerning symptoms.
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Scientific research related to this ingredient:
These research articles provide scientific evidence about Poloxamer 188 safety and effects.
Yes, Poloxamer 188 is generally considered safe for adults based on current research.
May harm organs like liver, kidneys, or lungs with repeated use.
Builds up in the body over time with repeated use.
Possible negative effects on the environment
Linked to long-term health effects after years of use or exposure.
Poloxamer 188 is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.
The appropriate age depends on the specific ingredient properties and concentration. This analysis is for adults. Use the age selector above to check other ages.
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