For adults: Polysorbate 80 is usually safe in creams and lotions when made by reputable manufacturers. Most health risks are low, but there is a notable concern that it can be contaminated during manufacturing with chemicals like ethylene oxide and 1,4‑dioxane, and it can sometimes irritate eyes or sensitive skin.
Choose products from trusted brands that test for impurities or state they are free of manufacturing contaminants. Do a small patch test on your inner arm before regular use. Avoid applying products with this ingredient to broken or irritated skin, and keep cosmetics out of your eyes. If you have sensitive skin, prefer formulations that state they are designed for sensitive skin or are fragrance-free.
Watch for redness, itching, stinging, or eye irritation and stop use if these occur. Be aware of contamination risks (ethylene oxide and 1,4‑dioxane) reported in ingredient safety reviews and government assessments—when concerned, look for products with independent contaminant testing or contact the manufacturer for test results. Also note that industry safety panels recommend limits on concentration and formulation to reduce irritation.
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This list shows products that contain Polysorbate 80 or its alternative names.
Yes, Polysorbate 80 is generally considered safe for adults based on current research.
Connected to cancer risk with long-term or repeated exposure.
Linked to long-term health effects after years of use or exposure.
Polysorbate 80 is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.
The appropriate age depends on the specific ingredient properties and concentration. This analysis is for adults. Use the age selector above to check other ages.
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