Symphytum Officinale Extract

Symphytum Officinale Extract molecular structure

adultsSkin contact product

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Is this safe for adults to use Symphytum Officinale Extract?

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USE WITH CAUTION
Danger Score: 5 (Lower is safer)
Quick Answer: Symphytum Officinale Extract use with caution for adults when used in topical products. Adults generally have higher tolerance.

ℹ️General Overview

For adults: This comfrey extract may be risky. It can carry plant toxins that have been linked to liver damage in people and to tumors in animal studies. Short, occasional use on unbroken skin is less risky than giving it to babies or using it for a long time, but caution is still needed.

What to Do

If you are an adult and the product contains this extract: use it only on unbroken skin, do not use it for long periods, and do not swallow it. Stop use if you have any signs of liver problems (yellowing of the skin or eyes, dark urine, unusual tiredness, nausea, stomach pain). Check product labels and prefer products that do not include comfrey extract. If you have liver disease, take medicines that affect the liver, are pregnant, or breastfeeding, talk with your doctor before using.

⚠️Warnings

Main warnings come from reports and health agency findings about pyrrolizidine alkaloids in comfrey and cases of liver injury after comfrey use, plus animal studies showing tumor formation. Because of these documented risks (including an advisory by a major health agency and published case reports), avoid applying this extract to broken skin, avoid long-term or repeated use, and never ingest products containing it.

Confidence: HIGH

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Safety Risk Labels

This ingredient has the following documented risks:

Cancer: Animal studies found tumors after exposure and lab tests show the plant extract can cause mutations in mammal cells. A national food safety agency has warned that comfrey may be a possible human carcinogen, so there is a real cancer risk with repeated or high exposure.
Organ Risk: There are multiple human case reports linking comfrey use to serious liver injury (hepatic veno‑occlusive disease). A national regulatory health agency has flagged comfrey as a known liver toxicant, so it can harm the liver with use.
Absorbed: The ingredient has been flagged for enhanced skin absorption and can carry harmful pyrrolizidine alkaloids into the body through the skin. That means the toxic chemicals can get into the bloodstream even when used topically.
Banned: A major food and drug safety agency advised manufacturers to remove comfrey products from the market because of safety concerns, and some product verification programs restrict its use. This shows it is restricted or removed in some regulatory settings.
Long-Term Risk: Because of documented liver damage in people and tumor formation in animals, repeated or long-term use raises the chance of serious health problems over time. Studies and regulatory actions point to lasting risk with ongoing exposure.

Tap or hover over labels to see detailed risk information.

Alternative Names for Symphytum Officinale Extract

This ingredient may also be listed as:

symphytum officinale extractSYMPHYTUM OFFICINALE EXTRACTSYMPHYTUM OFFICINALE (COMFREY) EXTRACTSYMPHYTUM OFFICINALIS EXTRACTEXTRACT OF SYMPHYTUM OFFICINALEEXTRACT OF COMFREYCOMFREY (SYMPHYTUM OFFICINALE) EXTRACTCOMFREY EXTRACT

Always check ingredient labels carefully, as ingredients may be listed under different names.

Common Questions About Symphytum Officinale Extract

Is this safe for adults to use Symphytum Officinale Extract?

Use caution with Symphytum Officinale Extract for adults. Some safety concerns have been identified.

What are the cancer risks of Symphytum Officinale Extract for adults?

Connected to cancer risk with long-term or repeated exposure.

What are the organ risk risks of Symphytum Officinale Extract for adults?

May harm organs like liver, kidneys, or lungs with repeated use.

What are the absorbed risks of Symphytum Officinale Extract for adults?

Can be absorbed through the skin and get into the bloodstream.

What are the banned risks of Symphytum Officinale Extract for adults?

Banned or heavily restricted in one or more countries.

What are the long-term risk risks of Symphytum Officinale Extract for adults?

Linked to long-term health effects after years of use or exposure.

What products contain Symphytum Officinale Extract?

Symphytum Officinale Extract is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.

When can adults using products with Symphytum Officinale Extract?

The appropriate age depends on the specific ingredient properties and concentration. This analysis is for adults. Use the age selector above to check other ages.

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