Tetrasodium Glutamate Diacetate

Tetrasodium Glutamate Diacetate molecular structurePubChem

adults • Skin contact product

Check for Different Age (6 available)

Is this safe for adults to use Tetrasodium Glutamate Diacetate?

✅
YES - Generally Safe
Danger Score: 1 (Lower is safer)
Quick Answer: Tetrasodium Glutamate Diacetate is generally considered safe for adults when used in topical products. Adults generally have higher tolerance.

ℹ️General Overview

For adults, this ingredient is generally considered low risk when used in normal skin products. It helps keep formulas stable. There are some safety notes in the scientific data, but most people tolerate it on normal, unbroken skin.

✅What to Do

Use products as directed. If you want extra caution, patch test a small area first. Avoid applying to open cuts, sores, or irritated skin. If you are pregnant, breastfeeding, or planning pregnancy, talk with your healthcare provider if you have concerns. Prefer products from brands that test for contaminants or that clearly state they screen ingredients.

⚠️Warnings

Watch for redness, stinging, or eye irritation after use — reports of irritation are limited but possible (European chemicals agency). There is limited evidence of genetic mutagenicity noted by the U.S. environmental agency and animal studies showing effects at high doses (Cosmetic Ingredient Review), and some concern about possible contamination with related chemicals (lists include nitrilotriacetic-type residues and sodium glycolate). Some product certification programs restrict use of this ingredient or require extra testing. If you notice any strong reaction, stop use and seek medical advice.

Confidence: MEDIUM

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Safety Risk Labels

This ingredient has the following documented risks:

Cancer: A U.S. environmental agency reported limited evidence that this ingredient can act as a mutagen. Mutagen findings raise concern because they can be linked to cancer risk with repeated or high exposure.
Organ Risk: A cosmetic safety review noted animal studies that showed changes in organ weights for mothers and their offspring at high doses. That points to possible harm to organs with repeated or large exposures.
Fertility: The same cosmetic safety review found evidence from animal studies of effects on mothers and offspring at high doses, which suggests possible developmental or reproductive effects.
Irritant: A European chemical agency found limited evidence this ingredient can irritate skin and eyes, and the ingredient file also notes possible irritation to skin, eyes or lungs. This can cause redness, stinging or discomfort on sensitive baby skin.
Absorbed: The ingredient record flags enhanced skin absorption. That means it can get through the skin and into the body more easily, raising the chance that the other risks above could reach internal organs.
Long-Term Risk: The ingredient file flags high contamination concerns (including chemicals such as nitrilotriacetic-type impurities) and also notes data gaps in safety testing. Contamination plus incomplete safety data raise concern for possible long-term health effects if exposure is repeated.

Tap or hover over labels to see detailed risk information.

Alternative Names for Tetrasodium Glutamate Diacetate

This ingredient may also be listed as:

tetrasodium glutamate diacetateTETRASODIUM GLUTAMATE DIACETATEL-GLUTAMIC ACID, N,N-BIS(CARBOXYMETHYL)-, TETRASODIUM SALTTETRASODIUM SALT L-GLUTAMIC ACID, N,N-BIS(CARBOXYMETHYL)-N,N-BIS(CARBOXYMETHYL)- TETRASODIUM SALT L-GLUTAMIC ACIDTETRASODIUM N,N-BIS(CARBOXYLATOMETHYL)-L-GLUTAMATE2-BIS(SODIOOXYCARBONYLMETHYL)AMINOGLUTARIC ACID DISODIUM SALT

Always check ingredient labels carefully, as ingredients may be listed under different names.

Products Containing Tetrasodium Glutamate Diacetate

This ingredient is found in the following products:

This list shows products that contain Tetrasodium Glutamate Diacetate or its alternative names.

Common Questions About Tetrasodium Glutamate Diacetate

Is this safe for adults to use Tetrasodium Glutamate Diacetate?

Yes, Tetrasodium Glutamate Diacetate is generally considered safe for adults based on current research.

What are the cancer risks of Tetrasodium Glutamate Diacetate for adults?

Connected to cancer risk with long-term or repeated exposure.

What are the organ risk risks of Tetrasodium Glutamate Diacetate for adults?

May harm organs like liver, kidneys, or lungs with repeated use.

What are the fertility risks of Tetrasodium Glutamate Diacetate for adults?

Some studies link this to future fertility or reproductive issues.

What are the irritant risks of Tetrasodium Glutamate Diacetate for adults?

Can cause skin redness, itchiness, or rashes—especially on sensitive baby skin.

What are the absorbed risks of Tetrasodium Glutamate Diacetate for adults?

Can be absorbed through the skin and get into the bloodstream.

What are the long-term risk risks of Tetrasodium Glutamate Diacetate for adults?

Linked to long-term health effects after years of use or exposure.

What products contain Tetrasodium Glutamate Diacetate?

Tetrasodium Glutamate Diacetate is commonly found in skincare products, cosmetics, and topical applications. Always check ingredient labels before use.

When can adults using products with Tetrasodium Glutamate Diacetate?

The appropriate age depends on the specific ingredient properties and concentration. This analysis is for adults. Use the age selector above to check other ages.

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